Reactions have included anaphylaxis, angioedema, hypotension, tachycardia, swollen tongue, dyspnea, wheezing and rash. Cerebrovascular Adverse Events, Including Stroke: In clinical trials with antipsychotic drugs, elderly subjects with dementia had a higher incidence of stroke including fatal stroke and transient ischemic attack vs placebo.
Ensure that the app is compatible with their specific smartphone Although most ingestions will be detected within 30 minutes, it may take up to two hours for the smartphone app and web portal to detect the ingestion of ABILIFY MYCITE; in some cases, the ingestion of the tablet may not be detected.
If the tablet is not detected after ingestion, do not repeat the dose [see Adverse Reactions 6 ]. The status of the MYCITE Patch is indicated by a status icon in the app to inform the user that the patch is properly adhered and fully functioning.
Instruct patients to ensure that the app is paired with the patch prior to use. Swallow tablets whole; do not divide, crush, or chew. Do not place the MYCITE Patch in areas where the skin is scraped, cracked, inflamed, or irritated, or in a location that overlaps the area of the most recently removed patch.
Instruct patients to keep the patch on when showering, swimming, or exercising. The app will prompt patient to change the patch and will direct patient to apply and remove the patch correctly.
Patients undergoing an MRI need to remove their patch and replace with a new one as soon as possible. If there is skin irritation, instruct patients to remove the patch. Dosage increases should generally not be made before 2 weeks [see Clinical Pharmacology The maximum recommended dosage is 30 mg daily; however, doses above 15 mg daily have shown no additional clinically meaningful benefit.
Dosage in Bipolar I Disorder The recommended starting dosage in adults with acute and mixed episodes associated with bipolar I disorder is 15 mg given once daily as monotherapy and 10 mg to 15 mg given once daily as adjunctive treatment with lithium or valproate.
The dosage may be increased to 30 mg daily based on clinical response. The maximum recommended daily dosage is 30 mg. The recommended dosage range is 2 to 15 mg daily.
Dosage adjustments of up to 5 mg daily should occur gradually, at intervals of no less than 1 week. The maximum recommended daily dosage is 15 mg. Periodically reassess to determine the continued need for maintenance treatment. Further information Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The dose can be increased to 3 mg on Day 2 1; Further dose adjustments can be made in mg or 3-mg increments, up to 6 mg/day, depending on clinical response and tolerability 1; The maximum recommended dose is 6 mg/day.
Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan.
Education can help friends and family understand the disorder and be more compassionate with the person who has it. Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves.
People with schizophrenia may seem like they have lost touch with reality.
Treatment of schizophrenia in adults (1) Maintenance monotherapy treatment of bipolar I disorder in adults (1) Only to be administered by intramuscular injection in the deltoid or gluteal mg and mg dose adjustments are obtained only by using the. Dose adjustments Administer half the dose when given with strong CYP2D6 or strong CYP3A4 inhibitors, or in patients who are known CYP2D6 poor metabolizers 1 Administer a quarter of the dose with the concurrent use of both strong/moderate CYP2D6 inhibitors and strong/moderate CYP3A4 inhibitors.
Dose Adjustments for CYP Considerations Refer to the prescribing information for oral aripiprazole for recommendations regarding dosage adjustments due to drug interactions, for the first 21 days when the patient is taking oral aripiprazole concomitantly with the first dose of ARISTADA.